Respiratory Disorders

COPD vs Asthma comparison, pneumonia types, TB management, chest tube care, and oxygen delivery devices with flow rates.

COPD vs Asthma

FeatureCOPDAsthma
OnsetGradual, age > 40Usually childhood/early adulthood
CauseSmoking (#1), alpha-1 antitrypsin deficiencyAllergens, exercise, cold air, stress
PathophysiologyChronic bronchitis (blue bloater): excessive mucus, productive cough. Emphysema (pink puffer): alveolar destruction, air trappingReversible bronchospasm, inflammation, mucus plugging
SymptomsProgressive dyspnea, chronic cough, barrel chest (emphysema), prolonged expirationEpisodic wheezing, dyspnea, chest tightness, cough (especially at night)
ReversibilityNot fully reversibleReversible with treatment
O2 TherapyLow flow (1–2 L/min) — hypoxic drive; high O2 can suppress respiratory driveAs needed during exacerbation
TreatmentBronchodilators, inhaled corticosteroids, smoking cessation, pulmonary rehab, O2 therapyRescue inhaler (SABA), controller (ICS), avoid triggers, peak flow monitoring

Inhaler Teaching

  • Use bronchodilator (SABA) before corticosteroid inhaler (opens airways first)
  • Wait 1–2 minutes between puffs
  • Rinse mouth after corticosteroid inhaler to prevent oral candidiasis (thrush)
  • Use spacer with MDI for better drug delivery

Pneumonia

TypeKey Features
Community-Acquired (CAP)Most common. S. pneumoniae #1 cause. Fever, productive cough, pleuritic chest pain, crackles. Treat with antibiotics (macrolide or fluoroquinolone)
Hospital-Acquired (HAP)Occurs ≥ 48 hrs after admission. Often resistant organisms (MRSA, Pseudomonas). Broader antibiotics needed
AspirationRisk: stroke, dysphagia, sedation, NG tubes. Prevent: HOB ≥ 30°, swallow evaluation, oral care
Pneumocystis (PJP)Immunocompromised (HIV/AIDS, CD4 < 200). Treat with TMP-SMX. Prophylaxis when CD4 < 200

Tuberculosis (TB)

Key Points

  • Airborne precautions (N95 respirator, negative pressure room)
  • Symptoms: persistent cough > 3 weeks, night sweats, weight loss, hemoptysis, low-grade fever
  • Diagnosis: PPD/Mantoux test (read in 48–72 hrs), QuantiFERON blood test, sputum for AFB (3 consecutive morning specimens), CXR
  • PPD positive: ≥ 5 mm (immunocompromised/HIV, close contacts), ≥ 10 mm (high-risk groups), ≥ 15 mm (low-risk)
  • Treatment: RIPE
    • Rifampin (red-orange body fluids; reduces effectiveness of oral contraceptives)
    • Isoniazid (INH) (monitor liver function; give with pyridoxine/vitamin B6 to prevent peripheral neuropathy)
    • Pyrazinamide (hepatotoxic; monitor uric acid)
    • Ethambutol (monitor vision — optic neuritis)
  • Treatment duration: 6–9 months minimum; directly observed therapy (DOT) recommended
  • Patient is non-infectious after 2–3 weeks of medication with negative sputum cultures

Chest Tubes

IndicationPlacement
Pneumothorax (air)2nd intercostal space, midclavicular line (air rises)
Hemothorax/Pleural effusion (fluid)5th–6th intercostal space, midaxillary line (fluid settles)

Chest Tube Nursing Care

  • Keep drainage system below the level of the chest at all times
  • Tidaling (water fluctuation) in the water seal chamber is normal (stops when lung re-expands)
  • Continuous bubbling in water seal = air leak (check connections)
  • Gentle bubbling in suction control chamber is expected
  • Never clamp a chest tube (risk of tension pneumothorax) unless briefly to locate a leak
  • If disconnected: place tubing end in sterile water (water seal)
  • If pulled out: cover site with petroleum gauze dressing taped on 3 sides
  • Monitor and document drainage (color, amount); notify if > 70 mL/hr (hemorrhage)

Oxygen Delivery Devices

DeviceFlow Rate (L/min)FiO2 DeliveredNotes
Nasal Cannula1 – 624% – 44%Most common; comfortable; patient can eat/talk. Each L adds ~4% FiO2
Simple Face Mask5 – 840% – 60%Minimum 5 L/min to prevent CO2 rebreathing. Remove to eat
Non-Rebreather Mask10 – 1580% – 95%Highest FiO2 without intubation. Reservoir bag must stay inflated (≥ 2/3 full)
Venturi Mask4 – 1224% – 50%Most precise FiO2; ideal for COPD patients. Color-coded adapters
Partial Rebreather6 – 1560% – 75%Reservoir bag allows rebreathing of first 1/3 exhaled air (high O2 content)
High-Flow Nasal CannulaUp to 60Up to 100%Heated, humidified; provides some PEEP effect